显微成像

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应用场景

医院微生物检验科

ICU病人超快速药敏检测

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疾控中心药敏检测

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畜牧养殖业耐药监测

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参考资料

1.Weili Hong, Caroline W. Karanja, Nader S. Abutaleb, Waleed Younis, Xueyong Zhang, Mohamed N. Seleem* and Ji-Xin Cheng* “Antibiotic Susceptibility Determination within One Cell Cycle at Single Bacterium Level by Stimulated Raman Metabolic Imaging.” Analytical Chemistry, 2018 (https://doi.org/10.1021/acs.analchem.7b03382)
2.Meng Zhang, Mohamed N Seleem, Ji-Xin Cheng, Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium, The Journal of Visualized Experiments, 2022 (https://pubmed.ncbi.nlm.nih.gov/35225259/)
3.Weifeng Zhang, Yun Li, Lin Yao, Fan Wu, Chen ChenLiqun Zhou, Bo Zheng, Pu Wang, Weili Hong, Rapid antimicrobial susceptibility testing by stimulated Raman scattering metabolic imaging and morphological deformation of bacteria, Analytica Chimica Acta, 2021 (https://doi.org/10.1016/j.aca.2021.338622)
4.Meng Zhang, Weili Hong, Nader S. AbutalebJunjie Li, Pu-Ting Dong, Cheng Zong, Pu Wang, Mohamed N. Seleem, Ji-Xin Cheng, Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium, Advanced Science, 2020 (https://doi.org/10.1002/advs.202001452)

基于相干拉曼技术,可以实现单个细菌的药敏检测

经过400多例临床菌种验证,准确率达到94.6%

高准确率

竞争优势

可以在一个细胞分裂周期内完成药敏检测

超快速

高特异性

混合菌种样本无需分离,同时检测不同细菌药敏

高灵敏度

CARSA超快速细菌药敏检测平台采用相干反斯托克斯拉曼散射显微成像技术,通过对细菌代谢的观测,将细菌药敏检测时间从2天缩短至2小时,且具备单细菌分析能力。产品适用范围覆盖绝大多数细菌和抗生素,与金标准对比一致性高。

产品简介

CARSA超快速细菌药敏检测平台

CARSA超快速细菌药敏检测平台基于对单细菌代谢的检测能力,能够颠覆性提高现有药敏检测的时效,快速且准确地为医生提供临床样品的药敏检测报告,为挽救危重病人的生命提供更多时间;该平台可重塑临床的抗生素管理流程,最大限度的降低预开广谱抗生素以避免抗生素的滥用,推进解决细菌耐药问题